The patient, a male, presented to the ENT department with hoarseness for 5 months and laryngoscopy suggested vocal cord granuloma, which was treated symptomatically several times but did not work. After detailed medical history, the patient had belching, burning sensation in the upper and middle abdomen, and foreign body sensation in the throat 5 years ago, with episodes about once a month and more frequent when the weather changed, and had gastroscopy suggesting chronic superficial gastritis, but did not pay attention to treatment; six months ago, he had discomfort in the upper and middle abdomen, and repeated gastroscopy suggesting erosive gastritis, but still did not pay attention to it; according to the patient’s digestive symptoms, gastroesophageal reflux disease was considered more likely, and because the patient could not Because the patient could not tolerate the examination, anti-reflux treatment such as PPI was given, and combined with ENT department to minimize pronunciation conditioning, in the 3rd week of treatment, the laryngoscopic granuloma disappeared on reexamination.