Hypoechoic nodules in the liver are considered to be hyperplastic nodules of the liver, which are common benign diseases that can be followed and observed regularly, and the formation of sterile inflammation secondary to repeated chronic inflammatory stimulation of hepatocytes. If the nodules gradually increase in size, the patient may also experience pain and discomfort in the liver area, so regular follow-up and observation are needed, and there are also some nodules that are prone to malignancy. If the nodules are found to have irregular margins or to grow rapidly in a short period of time, surgical treatment is required to remove the lesions and pathological examination is also required. In addition, some patients have cysts or hemangiomas in the liver, which may appear as hypoechoic lesions with an intact envelope and smooth surface and do not require special treatment.