There are 8 categories of people at high risk of pancreatic cancer: 1. family history of pancreatic cancer; 2. familial adenomatous polyposis, such diseases combined with pancreatic cancer are higher than the normal population; 3. over 40 years of age, non-specific symptoms in the upper abdomen, such as if there is no upper abdominal pain or persistent upper abdominal and low back pain of unknown origin, unexplained anorexia and wasting; 4. recurrent pancreatitis, chronic pancreatitis in a small percentage of patients in a small number of patients is an important precancerous lesion, especially chronic familial pancreatitis, chronic calcific pancreatitis; 5, sudden onset diabetes, especially atypical diabetes, age 60 years or older, no family history, no obesity, soon to develop insulin resistance, 40% of pancreatic cancer patients with diabetes at the time of diagnosis; 6, benign lesions after the majority of gastrectomy, especially those who are more than 20 years after surgery The incidence of pancreatic cancer is 1.65 to 5 times higher; 7. Melancholic psychosis without obvious causes; 8. Smoking, heavy drinking, occupational exposure (long-term exposure to harmful chemicals, etc.), long-term high-fat diet and obesity. Early detection of tumors is the key to get the best treatment effect, and pancreatic cancer is no exception. Although the proportion of clinically detected early stage pancreatic cancer is very low, but if we analyze these cases individually, we will find that the surgical resection rate of early stage pancreatic cancer is 90% to 100%, and the 5-year survival rate is 70% to 100%, compared with the progressive stage pancreatic cancer, there is a huge contrast between the two treatment effects.