Stage 3 Nephropathy represents that the kidney function has been damaged to a certain extent, which is relatively more serious, but active treatment is not terrible. Stage 3 Nephropathy is equivalent to the decompensated stage of renal failure, which may not have any uncomfortable symptoms, or some of them may have mild uncomfortable symptoms such as fatigue, lumbago, and increased urination at night. A few may also have anorexia, mild anemia, elevated blood pressure and so on. Patients with stage 3 nephropathy need to control risk factors such as blood pressure, blood glucose, and blood lipids, while hormone therapy, such as prednisone, and other immunosuppressant therapy, such as cyclophosphamide, cyclosporine, and tacrolimus, may be administered according to the type of pathology. Treatment is also needed to address the patient’s comorbidities, including anemia. Without active treatment, the disease may progress to stage 4 or 5 and enter end-stage renal disease, at which time dialysis treatment or kidney transplantation is required. In addition to medication, patients with stage 3 kidney disease should have a low-salt, low-fat, high-quality and low-protein diet, avoid overwork, etc. Meanwhile, they should undergo regular checkups, go to the hospital in time if they have any discomfort, and take active treatments under the guidance of the doctor to avoid the progression of the disease.