Antihypertensive drugs can be taken together with aspirin. Aspirin is an antiplatelet drug that can prevent the occurrence of thrombotic cardiovascular and cerebrovascular events with long-term use. In clinical practice, patients with hypertension who have a high probability of thrombotic cardiovascular events or who have cardiovascular disease often need to be given aspirin at the same time, when antihypertensive drugs and aspirin can be taken together. Since antihypertensive drugs and aspirin need to be taken in the early morning on an empty stomach, these two drugs can be taken together in the early morning on an empty stomach. Since aspirin can cause adverse gastrointestinal reactions, if you have significant gastrointestinal reactions, you can switch to an antiplatelet drug such as clopidogrel, which can also be combined with the antihypertensive drug.