It is best to wait until the antihypertensive medication is metabolized in the body before drinking alcohol. But taking antihypertensive drugs is a long-term process, such as taking twice a day or once a day long-acting preparations, so that the drug in the body can have a smooth effect and achieve the purpose of blood pressure control. Therefore, do not drink alcohol in this case, drinking alcohol may aggravate the adverse effects of the drug. Alcohol will make blood vessels dilate after it arrives in the body, which will aggravate the adverse effects of the drug, such as tachycardia, headache, hypotension, flushing, dizziness, nausea, and disorders of gastrointestinal function, and may even cause peripheral tissue edema, cough, pulmonary edema, and excessive lowering of blood pressure may also lead to ischemia of the brain and heart muscle. Therefore, alcohol should be prohibited while taking antihypertensive drugs.