Nifedipine Controlled Release Tablets can be switched to Amlodipine Benzenesulfonate. Nifedipine controlled-release tablets belong to calcium antagonists, which are mainly used in the treatment of patients with hypertension, and can be taken once a day to keep the blood pressure level stable throughout the day. Amlodipine benzenesulfonate is also a calcium antagonist, which is a long-acting agent with a similar mechanism of action as nifedipine controlled-release tablets, and can be replaced by amlodipine benzenesulfonate for patients taking nifedipine controlled-release tablets. The adverse reactions of nifedipine extended-release tablets and amlodipine benzenesulfonate are similar, and the common ones are lower limb edema, tachycardia, dry stools, facial flushing, etc. They are forbidden to patients who are allergic to the ingredients of the drug, or patients with severe aortic stenosis. When replacing nifedipine extended-release tablets with amlodipine benzenesulfonate, use the drug under the guidance of a physician and avoid self-adjustment.