Taking cephalosporin after drinking alcohol can trigger a disulfiram-like reaction, and if treated in time, it can usually relieve the symptoms and play a therapeutic role in 1-7 days. Firstly, if cephalosporin is a mild reaction after drinking alcohol, with only rash, itching, circumferential weakness, accompanied by the rash fusing into pieces and triggering rubella and wind cluster, timely application of drug treatment can be improved within 24-48 hours. Secondly, if there are circulatory system symptoms such as tachycardia, arrhythmia, myocardial ischemia, chest tightness, shortness of breath and discomfort in the precordial area after drinking alcohol and taking cephalosporin, it needs to be treated for 3-5 days to get better. Thirdly, if there is unstable blood pressure, reduced blood volume, unmeasured pulse, unconsciousness, or even coma shock, it should last for at least 7 days to be able to clinically improve.