Stroke is currently the third leading cause of death in China, after heart disease and tumors. It has been reported that about 29% of patients die within 1 year after stroke, and this percentage is even higher in people over 65 years old. Stroke is also the leading cause of disability, with 31% of stroke survivors requiring post-stroke care, 20% of stroke survivors requiring assistance to walk, and 16% requiring placement in a residential care facility. In addition, at least one third of stroke survivors have depression. The majority of stroke patients have ischemic strokes. It is only in recent years that significant advances in the treatment of ischemic stroke have allowed physicians to significantly improve the outcome of this devastating disease. Since the 1990s, as research into the pathophysiology of acute ischemic stroke and the rapid development of imaging technology have led to large-scale studies of thrombolysis in ischemic stroke at home and abroad. However, the progress of research is slow, and the promotion of thrombolysis is also slow, the biggest obstacle is that clinicians lack a deep understanding of the feasibility of thrombolysis and the time window for treatment. To reduce the extent of brain damage, promote functional recovery, and improve long-term prognosis after the onset of ischemic stroke, a therapy must be administered within a limited time frame. This permissible time limit is called the therapeutic time window. Currently, the concept of therapeutic time window is receiving increasing attention. The use of acupuncture in ischemic stroke rehabilitation has become more common, but because it is often applied late, the therapeutic effect varies greatly. We have conducted some clinical exploration on the time window of acupuncture treatment for ischemic stroke. The following observations are made. If the patient is not comatose at the onset of ischemic stroke, acupuncture treatment can be applied to the numbness, flaccidity or slurred speech of the limbs to limit the symptoms to a certain range and to reduce the symptoms and delay the limbs from entering the hard palsy stage, thus improving the long-term prognosis. Ischemic stroke can be treated by acupuncture when awake: for patients with ischemic stroke with shallow or moderate coma, acupuncture can be performed when awake, even before awake, as long as the condition is stable. For comatose patients, early application of acupuncture treatment is not only beneficial to the recovery of limb paralysis, but also can use Fengchi, Baihui, Renzhong, Yongquan and other points, acupuncture does not leave needles, to promote the patient awake. The relationship between the time window of acupuncture treatment and the efficacy of acupuncture treatment: how to define the time window of acupuncture treatment, there is not enough data to explain. Due to the individual differences in acupuncture, there are also individual differences in the time window of treatment, the time of acupuncture is different, and the therapeutic effect is also different. From the current clinical treatment effect, early intervention with acupuncture, together with functional exercise, has obvious effect. In patients with ischemic stroke, the choice of acupuncture treatment window needs to be further observed and studied, and whether the time of acupuncture intervention is directly proportional to the therapeutic effect also needs to be discussed. In conclusion, the clinical effect of early application of acupuncture in ischemic stroke patients is obvious, and it is important to draw the doctors’ attention to the concept of acupuncture treatment time window, and to observe, study and explore in the clinic to make qualitative changes and progress in the treatment of ischemic stroke. Our department uses “ultra early electro-acupuncture” to treat cerebrovascular disease, after clinical summary, scientific research, proved the effect of remarkable!