In the clinic, we often encounter such patients: “Doctor, I have a history of hypertension, and I usually take antihypertensive drugs. Recently, my blood pressure has been high and low, and I sometimes feel dizzy. What’s wrong?” After careful questioning, the patient said that his blood pressure was usually well controlled and that he could break up the antihypertensive medication and take half a tablet after hearing the introduction of his patients. After further inquiry, the patient was taking the antihypertensive drug nifedipine extended-release tablets. Why would breaking open a slow-release tablet lead to unstable blood pressure? Long-acting antihypertensive drugs vs. short-acting antihypertensive drugs Antihypertensive drugs are divided into long-acting antihypertensive drugs and short-acting antihypertensive drugs. Generally speaking, long-acting antihypertensive drugs are antihypertensive drugs that are taken less frequently each day, usually only once a day, and the drug effects are maintained in the body for a longer period of time. Short-acting antihypertensive drugs need to be taken several times a day, and the duration of antihypertensive effect is short. Short-acting antihypertensive drugs can cause sudden increase in blood pressure or even sudden cardiovascular death due to the short duration of drug effect or the patient’s omission. Long-acting antihypertensive drugs can maintain the blood pressure concentration in a longer period of time, which can play a more stable effect of maintaining blood pressure. Therefore, it is recommended that patients who need to take long-term antihypertensive drugs choose long-acting antihypertensive drugs. Slow-release, controlled-release tablets, can not be broken open to eat antihypertensive drugs in order to achieve the purpose of long-acting, often made into slow-release and controlled-release tablets, these slow-release and controlled-release tablets are controlled by a special controlled-release diaphragm drug release rate, when the drug is broken open, the diaphragm is destroyed, the drug’s slow-release system lost, the effect of rapid release in a short period of time, so that the effect of slow-release can not play a natural loss of long-acting The effect of long-acting antihypertensive drugs is lost. Which pills can be broken and eaten? 1, scored tablets: the simplest thing is to observe the surface of the tablets have no scores. The scoring itself is designed to break the tablets neatly, so the tablets with scoring can be broken open and taken along the scoring. 2, micronized release tablets: with micronized release and controlled release function of betalac extended release tablets can be broken open to take. Stabilize blood pressure and live a healthy life When blood pressure fluctuates, you should not mobilize antihypertensive drugs without permission, you should seek timely consultation with an experienced doctor, especially the antihypertensive drugs used by the elderly, you should always consult and listen to the doctor’s advice, do not think you can break or reduce and increase the dosage at will.