Hypertension is a major global public health problem, and the results of the 2004 China Population Nutrition and Health Survey show that the prevalence of hypertension among residents aged 18 years and above in China is 18.8%, with more than 200 million people suffering from the disease nationwide. Hypertension is a major risk factor for cardiovascular disease, and cardiovascular disease is the first cause of death among urban residents in China, o causing a heavy burden on individuals, families and society. Strengthening the management of hypertension is a matter of urgency. Early morning blood pressure: the key to cardiovascular and cerebrovascular events The diagnosis and treatment of hypertension is actually not complicated, but why after several years of efforts, there is still a big gap between the awareness rate, cure rate, and attainment rate of hypertension in China and developed countries. The 2010 Chinese guidelines for the prevention and treatment of hypertension state that antihypertensive treatment should effectively control nighttime and morning blood pressure in order to more effectively prevent cardiovascular complications. Human blood pressure is constantly changing and has a certain circadian rhythm, of which the time period with the greatest degree of blood pressure variability is early morning, generally referring to the time period of 6-10 a.m. Studies have found that the average rise in blood pressure of 14 mmHg can even rise by 80 mmHg, with blood pressure rising rapidly from a relatively low level to a higher level in a short period of time. Morning is the peak of cardiovascular events. Therefore managing early morning hypertension is is a leverage point to improve overall blood pressure management. Early morning blood pressure in hypertensive patients better reflects the patient’s daily blood pressure control, and long-term measurement and observation of early morning blood pressure compliance is important to improve blood pressure compliance and better prevent cardiovascular and cerebrovascular diseases. Just like the concept of 2-hour postprandial blood glucose in diabetes, it is important to pay attention to and manage patients’ early morning blood pressure and blood pressure before taking medication in order to more comprehensively assess patients’ blood pressure control, reasonably adjust treatment, truly achieve 24-hour smooth achievement, and better prevent cardiovascular and cerebrovascular diseases. The 2010 edition of the Chinese guidelines for the prevention and treatment of hypertension points out that priority should be given to the application of long-acting preparations: as far as possible, the use of long-acting drugs that are given once a day and effectively maintain 24 hours of antihypertensive effect, the use of stronger and longer duration and smooth antihypertensive drugs, given once a day in the early morning, can not only control the average level of blood pressure for 24 hours, but also effectively curb the blood pressure 18-24 hours (the last 6 hours) after taking the drug It is more effective in preventing cardiovascular and cerebrovascular complications. A large number of epidemiological and randomized clinical trials of blood pressure lowering have consistently confirmed that strengthening patients’ attention to and self-management of early morning blood pressure and pre-dose blood pressure, and applying a long-acting, once-a-day, smooth and lasting control of early morning blood pressure treatment plan can improve the blood pressure standard rate more quickly and effectively prevent cardiovascular and cerebrovascular events. China is a large country of hypertension, and the prevention and control of hypertension is the first line of defense in the prevention of cardiovascular and cerebrovascular diseases. Only by paying attention to and strengthening the management and control of blood pressure can we prevent problems before they occur. The basic principles of antihypertensive drug application 1, small dose: small dose to start, and gradually increase the dose as needed. 2.Dose application of long-acting agents: use long-acting drugs that are given once a day and have a sustained antihypertensive effect, in order to effectively control nighttime blood pressure and morning peak blood pressure. 3, the combination of drugs: to increase the antihypertensive effect without increasing adverse reactions. 4, individualized: according to the patient’s specific situation and tolerance and personal wishes or long-term affordability, choose the right antihypertensive drugs for patients. Antihypertensive drug varieties: there are five commonly used CCB, ACEI, ARB, diuretics, B-blockers.