Lung adenocarcinoma metastasized to the clavicle indicates that bone metastasis of lung cancer has occurred, which belongs to a kind of distant metastasis, indicating that the lesion has progressed to an advanced stage with a poor prognosis. The nature and frequency of symptoms of metastatic cancer are related to the size and location of the metastatic tumor. Metastasis to the clavicle may cause pain, pathological fracture, and may also lead to Horner’s syndrome, which is a syndrome caused by the compression of sympathetic nerves in the neck, including drooping eyelids, sunken eyes, absence of sweating in the forehead of the ipsilateral side, as well as pain of brachial plexus caused by compression of brachial plexus nerves, and so on. The treatment of stage IV patients is generally based on systemic therapy (chemotherapy or targeted therapy) combined with local radiotherapy, and surgery is no longer a treatment tool. In the case of incurable metastasis of lung cancer, palliative means, necessary pain relief and moderate nutritional support should be arranged to alleviate the pain and improve the quality of life.