Cracked corners of the mouth may be due to keratitis, eczema and other reasons, patients should go to the hospital as soon as possible for examination and treatment. 1. Keratitis: Keratitis is an inflammation that occurs at the joint of the upper and lower lips, patients usually have dry lips, erythema and edema at the corners of the mouth, usually due to bacterial infections, patients can use metronidazole, clotrimazole and other medications under the guidance of a doctor for treatment, allergic to this product is prohibited. 2. Eczema: eczema is caused by a variety of internal and external factors that cause intense itching of the skin inflammation, the patient’s wounds will appear itching, can be used under the guidance of a doctor, cetirizine, loratadine and other drugs for treatment, severe renal impairment of patients with the prohibition of this drug. If you have symptoms of physical discomfort, you should go to the hospital in a timely manner, under the guidance of a physician, give targeted treatment after the cause is clear, do not blindly use their own medication, and pay attention to hygiene in daily life.