There are more ways to confirm the diagnosis of drug-resistant TB. People considered at risk for drug resistance include patients who have had TB for many years, who are treated irregularly, and who use drugs repeatedly or stop and start using drugs. When people at high risk of drug resistance go to the hospital, the following methods are used to routinely confirm the diagnosis of drug resistance: 1. Sputum culture: The first step is the culture of sputum Mycobacterium tuberculosis, which takes a relatively long time, usually 45 days, and the results of the culture are positive, indicating the growth of Mycobacterium tuberculosis, and negative, indicating that Mycobacterium tuberculosis is not found. The Xpert test can not only distinguish between Mycobacterium tuberculosis and non-tuberculosis, but also detect whether the patient has rifampicin resistance, but cannot clarify whether the patient is resistant to other anti-tuberculosis drugs.