The rabies vaccine cannot be given as a single shot. Rabies vaccine is used to prevent rabies. Anyone who is bitten or scratched by a rabid dog or other rabid animal should be vaccinated with rabies vaccine in a timely manner according to the post-exposure immunization program. Under normal circumstances, the rabies vaccine requires five injections, usually the bitten person was 0 days, 3 days, 7 days, 14 days, 28 days, each injected with 1 dose of this vaccine. With only one dose of rabies vaccine, the body may not produce enough antibodies to fight against the rabies virus to provide the immunizing effect of the vaccine. Post-exposure immunization should follow the principles of timely, adequate and complete vaccination. Rabies vaccine is a biological agent, and symptoms such as redness, swelling, pain and itching may occur at the injection site after vaccination, which can usually be relieved on their own without stopping the vaccination. For some patients who develop allergic rash and purpura, they can go to the hospital and receive anti-allergy treatment to complete the whole vaccination. In addition, after the injection of rabies vaccine, you should avoid drinking alcohol, strong tea and other stimulating foods and strenuous exercise, to avoid aggravating the adverse reactions after vaccination and reduce the immune effect of the vaccine. Rabies vaccine can not be only one shot, it is recommended to strictly follow the standardized procedures for vaccination.