Rectal cancer is a common malignant tumor of the gastrointestinal system. Once bone metastasis occurs, the clinical stage of rectal cancer is stage IV, that is, late stage, and rectal cancer mostly reaches the bone through hematogenous metastasis, and the common sites of bone metastasis in clinical practice are spine, pelvis and other weight-bearing bones, and ribs. Once bone metastasis occurs in rectal cancer, it is mainly manifested as pain in the bone metastasis area, and some patients will have serious complications such as pathological fracture. Radiotherapy is mainly to symptomatically reduce symptoms and improve the quality of life, while the combination of chemotherapy and targeted drugs can play a synergistic role in anti-tumor treatment.