Thrombolytic therapy is an effective treatment for early cerebral infarction. Thrombolytic therapy includes intravenous thrombolysis and arterial thrombolysis, but there is a time requirement for thrombolysis, and the best time for thrombolysis is within 6 hours of disease onset. The commonly used thrombolytic drug is rt-PA, and ultra-early thrombolytic therapy within 4.5 hours of onset is mainly intravenous drug thrombolysis, after which arterial thrombolysis can be used to reduce the area of cerebral infarction and the disability rate of patients. For acute infarcts in large vessels, if they are not completely unblocked after thrombolysis, an interventional approach can be used to remove the thrombus from the infarct by using a guidewire to enter the intracerebral vessels from the artery at the root of the thigh. If the patient is still not treated with timely thrombolysis after 6 hours of onset, the interventional method of clot removal can be used directly. Treatment of cerebral edema is also performed, mainly by applying mannitol for dehydration, furosemide for diuresis, and infusion of human albumin for treatment. In addition, drugs can be used for neuroprotection, anticoagulation, and volume expansion, which can reduce the sequelae of cerebral infarction, and commonly used drugs include piracetam, ceruloplasmin hydrolysate, and low molecular heparin. Regardless of which treatment plan, it is to improve the blood circulation in the cerebral ischemic area in time, so try to carry out scientific and reasonable treatment in time within the golden 6 hours, so as to avoid the damage to the brain nerves of patients caused by cerebral ischemia and hypoxia, resulting in patients’ hemiparesis, etc., which will seriously affect the quality of life of patients and their families.