With the development of economy and improvement of quality of life, especially the proportion of patients with end-stage renal disease caused by diabetes is gradually increasing, causing the total number of patients with end-stage renal disease (uremia) in China to increase from 2014 to 2017.In 2014, the total number of patients with end-stage renal disease in China was 2.16 million, which increased to 2.57 million in 2016 and reached 2.9 million people. The rapid increase of patients with uremia has brought a heavy burden not only to individuals and families, but also to the country. Therefore, early recognition of the triggers of uremia and learning to avoid the various triggers of uremia are of great importance to prevent and delay the occurrence of end-stage renal failure. Today, we recommend an article which tells you that some factors in daily life may cause kidney damage and bring progressive damage to kidney function. You can benefit from knowing them as early as possible. Uremia (also known as end-stage renal disease) is a common outcome of chronic kidney disease, but not all chronic kidney disease progresses to uremia. So, what factors can trigger uremia? 4 major factors that can trigger uremia 1, kidney disease Kidney disease is the main cause of uremia, early kidney disease patients do not pay attention to lifestyle habits, often accelerating the development of the disease, especially staying up late, working hard, overeating and other bad habits, more likely to cause uremia. 2, hypertension Uremia is a common complication of hypertension, so patients with hypertension should actively cooperate with treatment to control blood pressure and improve the condition. 3, urinary infection urinary infection and uremia have a certain relationship, whether male or female may induce uremia. In China, chronic pyelonephritis is the second factor of uremia, accounting for 21.2%, married women are more likely to suffer from urinary sensation, and their risk of developing uremia is greater. 4, diabetes Diabetic nephropathy is the most common complication of diabetes, and diabetic nephropathy is a situation in which uremia occurs, especially in patients whose glucose tolerance is relatively low, inducing uremia is a high probability of occurrence. Many people have irregular diets, especially kidney function, which also causes more and more people to have uremia. Clinical symptoms The clinical manifestations of uremia are similar to the clinical manifestations of chronic kidney disease, which also means that some kidney disease patients who progress to renal failure may not be found to have developed uremia. Therefore, patients with kidney disease must undergo regular blood and urine tests to assess kidney function. Common clinical manifestations of uremia are: How to treat Uremia is treated by removing the underlying causes, such as removing kidney stones, controlling autoimmune diseases, diabetes and hypertension. Ensuring adequate nutrition is also the key to the dietary management of uremic patients, but overnutrition should be avoided. Because excess nutrition will produce too many metabolic end products that cannot be completely excreted, resulting in excessive accumulation in the body. Reducing protein intake can reduce the risk of urotoxicity and metabolic toxicity, but a balanced nutrition and strict implementation of a low protein diet should be ensured.