The HPV injection is not recommended because HPV injection is an external antigen, once injected into the body, it is easy to induce an acute attack of allergic rhinitis, or even induce local or systemic allergy, which is not safe. 2, the patient is an acute rhinitis attack, also known as The common cold period, at this time is also not recommended to play. Because the common cold period means that the patient’s resistance is particularly low, if this time to play HPV injection, because the patient’s immunity is not sound easily induced by the emergence of local immune response, and the patient’s body is also not good. The efficacy of the needle may be affected to a certain extent during the period of decreased resistance.3. Some patients are chronic rhinitis episodes, at this time it is recommended to consult a doctor, in fact, there is no absolute contraindication.4. Some patients are dry rhinitis, atrophic rhinitis, this time can be appropriate to play HPV needle, the specific circumstances need to be combined with the patient’s personal situation and the doctor’s decision to determine.