Mucus and phlegm in the throat with shortness of breath may be caused by acute pharyngolaryngitis, chronic bronchitis, chronic obstructive pulmonary disease and acute pneumonia. 1. Acute pharyngolaryngitis: acute inflammation of the throat leads to local congestion and increased secretions, so there is mucus in the throat, sore throat, and some patients have high fever and shortness of breath. 2. Chronic bronchitis: chronic inflammation of the bronchial tubes for a long time, there can be mucus in the throat, accompanied by shortness of breath, cough and other symptoms. 3. Chronic Obstructive Pulmonary Disease (COPD): Most of the cases are due to air pollution and prolonged smoking which leads to chronic inflammation in the lungs, causing symptoms such as coughing, sputum, shortness of breath and dyspnea. 4. Acute Pneumonia: Acute inflammation of the lungs can cause coughing, coughing up sputum, resulting in mucus in the throat with shortness of breath, dyspnea, fever and other symptoms. Mucus in the throat with shortness of breath has many causes, it is recommended to consult a doctor in time to identify the cause of the disease and follow the doctor’s instructions.