Hepatitis B vaccine is currently domestically produced by manufacturers such as Shenzhen Kangtai Biologicals and Beijing Tiantan Biologicals. Hepatitis B vaccine is used to prevent hepatitis B virus. At present, the main domestic manufacturers of hepatitis B vaccine are Shenzhen Kangtai Biological Products Company Limited, Beijing Tiantan Biological Products Company Limited, and Dalian Hanxin Biological Pharmaceutical Company Limited. Usually, hepatitis B vaccine requires three injections, one each at 0, 1 and 6 months of age. Hepatitis B vaccines from different manufacturers can stimulate the body to produce corresponding antibodies to a certain extent as long as they are regularly produced. It should be noted that whether antibodies can be produced after hepatitis B vaccination varies from person to person, most people can produce antibodies, while some people cannot successfully produce antibodies. It is necessary to consult a specialized doctor. In addition, people with hepatitis, fever, acute illness, acute exacerbation of chronic diseases, or history of allergy should avoid hepatitis B vaccination.