Hepatitis B vaccination can effectively prevent hepatitis B virus infection. The current hepatitis B vaccine is a genetically engineered vaccine, which is safe and reliable. Although some mild reactions may occur after hepatitis B vaccination, most of them do not require treatment and can be relieved on their own, and there are no special contraindications. Hepatitis B vaccination procedure: 3 doses in total, according to the 0, 1, 6 months procedure, i.e. after the first vaccination, the second and third vaccinations are given at intervals of 1 and 6 months. The vaccination site is intramuscular in the anterior lateral thigh for newborns and intramuscular in the middle of the deltoid muscle of the upper arm for children and adults. After vaccination, the reaction is generally mild, but some people may have symptoms such as low fever, redness and swelling at the vaccination site, pressure pain, etc. The incidence of heavy arm acidity or fever, nausea, vomiting, malaise, rash, etc. is roughly similar to that of general vaccination, and most of them will recover within 1 to 3 days without treatment. Hepatitis B vaccine can be given at the same time as the flu vaccine, BCG vaccine, Bacille Calmette-Guérin, polio vaccine, and brain B vaccine, but it is best not to use it at the same time as the measles vaccine. The current hepatitis B vaccine is genetically engineered, safe and reliable, but if you use substandard products, such as injecting damaged or spoiled vaccine, or if the injection process is not operated according to the aseptic requirements, or if you share syringes or needles, you can contract hepatitis or other infectious diseases. It is worth noting that people with serum disease, bronchial asthma, allergic urticaria and allergy to some drugs such as penicillin and sulfonamide are prohibited from receiving hepatitis B vaccine; newborns born abnormally with low weight, premature birth and caesarean section are temporarily not suitable for receiving hepatitis B vaccine, and it is better to postpone the vaccination. Therefore, hepatitis B vaccine is highly safe, and in general, daily work and life will not be affected after hepatitis B vaccination, and a few people have mild reactions at the vaccination site, which can be relieved by themselves sooner and do not need special contraindications.