Anal fissure can be cured by general treatment, medication and surgery. 1. General treatment: patients can use 1:5000 potassium permanganate solution for warm water sitz bath after defecation, usually increase the amount of drinking water, eat more fiber-rich food, avoid spicy and stimulating food, keep the bowel movement, avoid dry stools and dry. 2. medication: when the stool is not discharged smoothly, you can use laxatives to relieve, commonly used drugs are lactulose, Ma Ren Lunji pill, etc., constipation can also be used in serious cases of Keseru or enema treatment. If the pain of anal fissure ulcer surface is combined with infection, you can apply erythromycin ointment, lincomycin ointment and other anti-infective treatment after local debridement. 3. Surgery: Patients with anal fissure can have the lesion removed by anal fissure resection; they can also be treated by internal anal sphincter amputation, which can alleviate the symptoms of pain and cure the recurrence of anal fissure. It is recommended that patients with anal fissure should go to the hospital in time and choose the appropriate treatment plan under the guidance and operation of professional doctors. The treatment needs to be strictly follow the doctor’s instructions for medication and implementation.