In recent years, cranial defects appear frequently in our sight, more and more people because of various reasons unfortunately lead to a part of the skull defect, the area of the defect is large or small. Mr. Wang from Anhui Province had a traffic accident, craniectomy decompression surgery led to cranial defect 10cm * 10cm, this matter to Mr. Wang’s physical and psychological damage, not only the head collapsed unsightly, memory is also a significant decline, and sometimes also dizziness and headache. Later, after inquiring through various channels, he learned that our team used an advanced peek material to repair the skull for the majority of patients with very good results, so he came to the hospital in the name of Mr. Wang. Based on Mr. Wang’s cranial CT data, we customized his 3D reconstruction with a polyetheretherketone cranial patch. Subsequently, Mr. Wang underwent peek cranioplasty, in which the 3D customized PEEK patch was precisely fitted into the bone window and the surgery was successfully completed. After the surgery, Mr. Wang’s skull shape was restored and he was in a much better mood. In fact, Mr. Wang initially planned to have the titanium mesh skull repair done in the local hospital, but he learned that titanium mesh still has some disadvantages, and there is a high rate of postoperative rejection and infection, as well as the possibility of titanium mesh exposure. In order to be safer, he chose to come to Aviation General Hospital for peek cranioplasty. What should a patient who has chosen titanium mesh for cranioplasty do if the mesh is exposed after surgery? In this case, it is recommended that the patient go to a professional cranial bone repair hospital in time to take out the titanium mesh and choose peek material to do the second repair. The seriousness of the skull defect is self-evident, first of all, the image of the whole person will be greatly affected, and it will also lead to a series of safety problems. Therefore, after the skull defect must not escape, patients and their families should fully realize that it will bring great harm, as soon as possible to go to the regular hospital to do peek cranial repair plastic surgery, so that their skull as soon as possible to restore the integrity of their own to open up a whole new life for themselves.