Lumbar disc herniation does not usually lead to left hand weakness; left hand weakness may be caused by peripheral nerve entrapment, cervical spondylosis, and high central pathology. Treatment mainly includes conservative treatment and surgical treatment. 1. Conservative treatment: patients with tenosynovitis, carpal tunnel syndrome, elbow tube syndrome and other diseases need to carry out braking of the affected limbs, reduce the upper limb heavy physical activity, and also can carry out hot compresses, physiotherapy and other ways to accelerate blood circulation; patients with cervical spondylosis can choose traction, oral drugs such as methylcobalamin, vitamin B1, etc, to reduce the oedema compression and nutritional nerves. Patients with cerebrovascular accident can also choose hyperbaric oxygen chamber treatment. 2. Surgical treatment: mainly for patients with spinal cord cervical spondylosis, patients with stenosing tenosynovitis and tenosynovial cysts. These diseases usually cause mechanical entrapment of peripheral nerves or spinal nerves, resulting in weakness of the left hand, and surgical intervention is recommended. Surgical modalities such as myeloablation, release surgery, and lumpectomy are available. The specific surgical procedure will depend on the patient’s primary condition. If the symptoms of left hand weakness are not relieved, or accompanied by other symptoms, the patient should go to the hospital in time, and the cause should be clarified and targeted treatment should be given. The above drugs should be used under the guidance of a doctor, avoid self-medication.