Lumbar 1 vertebral compression fracture with bone marrow edema should go to the hospital for comprehensive examination and treatment. Minor compression fracture can be treated conservatively, while severe cases can be treated surgically. Lumbar 1 vertebral compression fracture mainly occurs in middle-aged and old people with osteoporosis, and bone marrow edema can be caused by compression fracture when the elderly are subjected to minor violence. After a compression fracture occurs, it is important to go to the hospital for a thorough examination and treatment to avoid complications caused by delayed treatment (nerve damage, long-term chronic pain, etc.). Minor compression fracture can be treated conservatively. Conservative treatment consists of strict bed rest for 2~3 months, symptomatic use of non-steroidal anti-inflammatory drugs for pain relief (e.g. Celecoxib, etc.), and use of drugs such as Mazolin to reduce the oedema (however, the use of the drugs should be under the guidance of a doctor). Surgery can also be used if symptoms are severe or if there is nerve damage. The main types of surgery are minimally invasive surgery and open surgery. Medications should be prescribed by your doctor.