Spot on the face can be caused by genetic factors, ultraviolet radiation, improper skin care, exposure to irritating substances and other reasons. 1. Genetic factors: such as nevus of Ota and coffee spot are congenital spots, which are caused by genetic factors; 2. UV radiation: if the skin on the face is exposed to sunlight for a long time and does not pay attention to sun protection, the skin will secrete a lot of melanin to form pigmentation and produce dark spots after long-term exposure to UV radiation; 3. 3, improper skin care: long-term use of poor quality skin care products, or improper skin care after makeup is not cleaned up, may cause spots on the face; 4, irritating substances: frequent contact with some strong irritating substances may lead to skin allergies, allergic reactions can be left after pigmentation; 5, drug factors: such as chlorpromazine hydrochloride tablets, phenytoin sodium tablets and other photosensitive drugs, the skin in the sun Hormone level abnormalities: endocrine disorders due to mental stress, frequent late nights, endocrine system diseases such as pituitary gland and thyroid gland abnormalities, female pregnancy, ovarian diseases and old women after menopause will lead to changes in hormone levels, which may cause skin metabolic disorders and may lead to spots on the face. If the color of the spots on the patient’s face is light, the area is small and there are no other physical signs, the patient can be temporarily observed and pay attention to rest and daily protection. If the spots on the patient’s face are large, multiple or dark in color, or accompanied by itching, pain and other uncomfortable symptoms, the patient should go to the dermatology department of the hospital for consultation in time.