Artificial oxalic metronidazole is not recommended to be applied directly to the teeth. The drug its method of use is oral, due to the teeth can not directly absorb artificial oxalic metronidazole, direct application on the teeth is not effective, so it is not recommended to apply directly on the teeth. Artificial oxalic metronidazole is mainly used for the treatment of acute wisdom tooth pericoronitis, localized alveolar abscess, pulpitis, apical periodontitis and so on. Adverse reactions such as nausea, loss of appetite, urticaria, dizziness, etc. may occur after use, and seizures and peripheral neuropathy may be caused by high doses, so it is recommended to stop the medication in time and seek medical attention. Patients who are allergic to metronidazole or pyrroles, patients with active central nervous disorders and blood disorders, pregnant women, patients who drink alcohol need to be prohibited. Patients are advised to use Artificial Oxalic Metronidazole under the supervision of a doctor and not to use it privately.