The difference between Rucker’s cyst and astrocytoma mainly lies in the source, site of occurrence, nature and other differences. 1. Source: Rucker’s cyst originates from the residual tissue of Rucker’s pouch in the saddle region, while astrocytoma originates from astrocytes. 2. Site of occurrence: Rucker’s cyst occurs in the saddle region, while astrocytoma can occur in any part of the central nervous system. 3. Nature: Rucker’s cysts are non-neoplastic, with a cyst wall consisting of a single layer or pseudocomplex epithelium. Most cysts are very small and do not cause symptoms, while a few gradually increase in size and compress the intra- or suprasellar structures, causing clinical symptoms. Astrocytomas are infiltrating growing tumors that are mostly malignant. Lacunar cysts are very different from astrocytomas. If you have any disease, you should go to a regular hospital in time for further examination and treatment under the guidance of a professional doctor.