HC2 and HPV are both used to detect HPV infection, but there are some differences. In clinical testing, it is more common to use morphological methods to detect HPV, which is the common HPV test used in gynecology to inform whether there is HPV infection and what type of infection it is, but there is no specific value. HC2, on the other hand, is a quantitative test, which can detect 13 high-risk types of HPV at the same time and will not be specifically typed, but only inform the amount of 13 types of HPV. The specificity, positive and negative predictive values of HC2 are very high, and it has become the gold standard for various HPV tests, but because it cannot determine specific typing, it also has certain defects, but no matter which HPV test However, no matter which HPV test is used, it is of great importance for cervical cancer screening.