Patients who stay up late for a long time will cause cerebral blood supply insufficiency: first of all, those who stay up late for a long time will experience sympathetic over-excitement, and when sympathetic tone increases, it will lead to increased myocardial contractility, increased cardiac conduction velocity, and increased oxygen consumption of the heart, therefore, the patient will have insufficient myocardial blood supply, and cerebral vascular insufficiency in the case of long-term insufficiency of myocardial blood supply, which will lead to the ischemia of the peripheral target organ organs. It will trigger the occurrence of cerebral arterial blood supply insufficiency. In addition, when staying up late for a long time, the patient will also have hypersecretion and activation of the renin-angiotensin aldosterone system, which will lead to a rise in blood pressure under the condition of increased aldosterone secretion, and therefore will further cause cerebral blood supply and cerebral circulation disorders. In addition, prolonged staying up late will also cause disorders of the neurohumoral-endocrine system, which will also cause insufficient blood supply to the cerebrovascular system.