There is no conflict between the two medications, Artificial Oxalic Metronidazole and Tadalafil, when they are used and they can be taken at the same time. Artificial Bovine Metronidazole is mainly used to treat acute wisdom tooth pericoronitis, localized alveolar abscesses, pulpitis, and apical periodontitis. Adverse reactions such as seizures, peripheral neuropathy, nausea and vomiting, diarrhea, abdominal discomfort, headache, and dizziness may occur with the use of this medication. It is contraindicated in patients who are allergic to metronidazole or pyrroles, patients with central nervous disorders and blood disorders, pregnant women and alcohol drinkers. The use of artificial oxalic metronidazole need to pay attention to, should not drink alcoholic beverages during the use of medication; hepatic hypoplasia the metabolism of the product slows down, should be used in reduced quantities and blood concentration monitoring; Candida infected patients with the application of the product, need to be given at the same time antifungal treatment. Tadalafil is used to treat symptoms of erectile dysfunction combined with benign prostatic hyperplasia. Adverse reactions such as headache, dyspepsia, back pain, myalgia, nasal congestion and flushing may occur with the use of this drug. The drug is contraindicated in patients who are taking nitrates and in patients with a known allergy to tadalafil. When using tadalafil, it should be noted that the drug is not recommended for patients who have had a myocardial infarction within 90 days and a stroke within the past 6 months; tadalafil may cause a transient decrease in blood pressure. Both of these drugs should be used under the supervision of a doctor.