It is possible to wake up after 30 days in a coma with amniotic fluid embolism, which needs to be evaluated by a doctor. The cause of amniotic fluid embolism is still unknown and may be related to high pressure in the amniotic cavity, breakdown of the maternal-fetal barrier, opening of blood sinuses, rupture of the fetal membranes, and other factors. The main symptoms are sudden onset of hypoxemia, low blood pressure and coagulation disorders, which can usually be characterized by dyspnea, breath-holding, chills, coughing and dizziness in the early stages. Then cardiopulmonary failure, shock, coagulation dysfunction, some patients can appear long-term coma, and even life-threatening. After 30 days of amniotic fluid embolism coma, it indicates that the brain function is severely damaged. The subsequent awakening depends on the recovery of brain function. Due to the abnormal complexity of the human brain, some patients can spontaneously awaken, but most patients will experience persistent coma or further deterioration of their condition leading to death. Therefore, in the event of amniotic fluid embolism, it is recommended to seek medical attention and receive treatment from a doctor without delay.