Postpartum hemorrhage amniotic fluid embolism, clinical incidence of amniotic fluid embolism (1.9-7.7)/100,000, mortality rate of 19-86%, coupled with postpartum hemorrhage mortality rate will be even higher, once the occurrence of the need for active resuscitation, did not look for data on the survival rate of the two occurring at the same time. Postpartum hemorrhage is caused by obstruction of uterine contraction, which is relatively common in clinical practice and is the first cause of maternal mortality in China. Amniotic fluid embolism is caused by the entry of amniotic fluid into the blood circulation, which leads to a series of physiopathologic changes such as pulmonary hypertension and circulatory failure. Amniotic fluid embolism is characterized by an acute onset, aggressive, unpredictable, and high-risk clinical features, but is clinically rare, with a mortality rate of 19-86%. When these two situations occur, both need immediate rescue, both at the same time more difficult to increase the rescue treatment, clinical supplementation of blood volume, increase oxygenation, anti-allergy, correct coagulation dysfunction, etc. for rescue treatment. It is recommended that pregnant women choose regular medical institutions for delivery to prevent accidents during delivery. Large-scale professional medical institutions have better countermeasures for emergencies, which can maximize the preservation of the lives of pregnant women and fetuses.