Ground glass nodules may appear suddenly over the course of a year. The appearance of ground-glass nodules includes both infectious and non-infectious factors, and the next step in management or treatment should be decided based on factors such as the patient’s clinical presentation and the size of the ground-glass. Recent bacterial, fungal, viral, tuberculosis and other infections can cause inflammatory exudation from the lungs, which will show up as ground-glass nodules on imaging; it may also be due to cancerous transformation of lung tissue cells within one year, which will also be detected as ground-glass nodules on physical examination. If there is no obvious clinical manifestation of ground-glass nodules within one year and the nodules are small, no special treatment is needed, and only observation and follow-up are necessary; if there is emaciation, weight loss, anemia, large nodule diameter, or the nodules have the tendency of malignant transformation, further examinations such as fine-needle aspiration can be done to clarify the nature of the nodules and to formulate an appropriate treatment plan. Therefore, if ground-glass nodules appear within one year, patients should go to the hospital in time to improve the examination, to clarify the nature of the nodules, and to deal with them as soon as possible.