If repeated breath-holding and chest tightness are caused by large amount of pleural effusion and pulmonary atelectasis, active puncture and fluid extraction, closed chest drainage and chest perfusion chemotherapy if necessary are needed to better control the growth of pleural fluid to relieve the symptoms of breath-holding. But the survival period is generally not effectively prolonged, and is still generally about one year. If breath-holding and breath-holding belong to combined cardiovascular disease, the survival cycle needs to be assessed according to whether the cardiovascular disease is combined with coronary heart disease, myocardial ischemia and angina pectoris. If there is no acute myocardial infarction, the survival cycle of lung cancer is usually about one year. If advanced breath-holding is mainly due to long-term cachexia, bed-ridden, severely reduced cardiopulmonary function and malnutrition, giving necessary nutritional fluids as well as blood transfusion treatment, including human albumin and blood transfusion, can temporarily relieve nutritional status and improve survival quality, but it does not have much impact on the overall survival period, which is still generally about one year, so the overall survival period of advanced breath-holding in lung cancer is generally about one year.