Macroglossia is a common eye disorder caused by infection of the glands at the lid margin, resulting in localized redness, swelling, pain, and sometimes nodules and granulomas on the eyelids. It is more common in the adolescent population. The main treatment options are local medication in the early stages and surgery in the later stages if medication is not satisfactory. The medication for wheals seeds is localized with antibiotic drops and eye ointment in the acute stage, and eye ointment with hormones can be used appropriately in the receding inflammation period, and hot compresses can be applied to promote the dissipation of the lumps. In general, oral antibiotics are not required. For patients whose infection has spread to the soft tissues of the surrounding eyelids, and for those with low resistance (elderly, diabetic, long-term immunosuppressant use, etc.), antibiotics may be administered orally or intravenously. Macroglossia is cured in most people after treatment with medications. If medication is not effective, surgery can be used. The specific surgical procedure depends on the location of the wheals. If the bulge is on the outside of the eyelid, the surgical incision needs to be made from the outside, and if the swelling is on the conjunctival surface, the surgical incision needs to be made on the conjunctival surface.