There is no quick fix for an upset stomach. Tummy discomfort is related to physiological factors such as not paying attention to abdominal warmth, improper diet, etc., and does not require special treatment. It is also considered to be related to acute enteritis, intestinal polyps, acute appendicitis and other diseases, which need to be treated with medication or surgery as prescribed by the doctor. 1. Physiological factors: not paying attention to abdominal warmth, eating food that is not easy to digest, such as fried chicken, etc. can lead to stomach discomfort. Usually no special treatment is needed. It can be relieved by proper massage and drinking warm water. 2. Acute enteritis: Usually patients can follow the doctor’s instructions to apply bifidobacteria, Saccharomyces boulardii and other microbial preparations for treatment, and can also apply montmorillonite to achieve the purpose of protecting the intestinal mucosa. If it is caused by bacterial infection, it can be treated with antibiotics such as norfloxacin and ciprofloxacin as prescribed by the doctor. Taking serious cause spasm can be used belladonna, atropine and other antispasmodic relief. 3. Intestinal polyps: When intestinal polyps induce stomach discomfort, you can seek medical treatment by endoscopic polypectomy, endoscopic mucosal resection and other surgical methods. Usually there is no special medicine to treat intestinal polyps, and when accompanied by infection, you can use penicillin, cefixime and other anti-infective drugs as prescribed by the doctor. 4. Acute appendicitis: some patients can first take conservative treatment, such as the application of ampicillin, gentamicin and other antibiotics to control the infection, pain can be used with buprivastigmine, pethidine and other analgesics. For patients with serious conditions, early surgical removal of the appendix is required. There are many reasons for stomach discomfort, it is recommended to follow the doctor’s instructions after the cause of the disease is clear, do not use drugs on your own to prevent aggravation of the condition.