Cranium is a hard and indispensable bone in the human body, which plays a pivotal role in the normal operation and health of human life activities. When the cranium itself is diseased due to external factors or the cranium itself, it will cause cranial defects, which will break the normal trajectory of people’s life and reduce the quality of life. Cranial defect is a very common cranio-cerebral disorder, patients due to atmospheric pressure to make the local scalp subsidence, may lead to intracranial pressure imbalance, brain tissue displacement, as well as cerebral hemisphere blood flow reduction and cerebrospinal fluid circulation disorders, which causes a series of clinical manifestations, mainly including: headache, vertigo, irritability, epilepsy, no other reason can be explained by the feeling of discomfort and a variety of mental disorders. Therefore, patients with cranial defects must have timely cranial repair. Good repair materials can improve the success rate of surgery and reduce the pain of patients. At present, the new PEEK material is used as the cranial bone repair material, which is shaped according to the patient’s cranial CT data and highly restores the physiological structure of the skull. In addition, the innovative introduction of the concept of plastic surgery, combined with the unique design of the mesh aperture and the unique intraoperative tissue separation and reset technology, effectively avoiding temporal muscle atrophy, to ensure the activity of the tissues, to ensure that the postoperative guarding the symmetry of the head, to achieve the purpose of a natural and beautiful appearance.