1, the patient’s mentality is not correct will affect psoriasis treatment Many patients do not adjust their mentality, always can not be positive, optimistic to treat the disease, coupled with the daily diet is not good taboos, wet and cold living environment can not be improved in a timely manner and other factors, will lead to psoriasis treatment effect greatly reduced. 2, the patient’s lack of understanding of the disease will also affect psoriasis treatment If psoriasis patients then lack a correct understanding of the disease, it is easy to give themselves greater pressure. In the treatment process because of the eagerness to cure by some advertising or the temptation of charlatan doctors, experienced a lot of twists and turns in the psoriasis treatment road, such as the use of glucocorticoids, immunosuppressive drugs, anti-tumor drugs and even some heavy metal drugs, these drugs are characterized by immediate results, immediately can change the status quo, but then is inevitable relapse, more importantly, will give the whole body However, they are followed by inevitable recurrence, and more importantly, they can bring serious consequences to the whole body or some organs of the system. The following treatment principles are followed: (1) Regularity: Emphasis is placed on the use of currently accepted therapeutic drugs and methods in the dermatological sciences. (2) Safety: All treatment methods should ensure the safety of patients as the first priority, and serious adverse reactions should not occur in the pursuit of immediate efficacy. Patients should not be made to apply methods that are harmful to their health for a long time without medical guidance. (3) Individualization: When choosing a treatment plan, the condition, needs, tolerance, affordability, previous treatment history and adverse reactions of drugs of patients with psoriasis should be considered comprehensively and reasonably chosen to formulate a treatment plan. I. Topical drug treatment Mild protective agents and emollients are appropriate in the acute stage of psoriasis; stronger drugs are available in the stable and receding stages, but they should start from low concentrations. Second, physical therapy Narrow-spectrum UVB: medium-wave ultraviolet ray with wavelength 311rim (308, 310, 311, 312am). It has good efficacy in the treatment of psoriasis and little side effects such as erythema, hyperpigmentation, DNA damage and carcinogenesis. Narrow-spectrum UVB treatment is better than broad-spectrum UVB, and safer than PUVA treatment. Anti-infective drugs: Bacterial, viral or fungal infection is an important cause of psoriasis, and infection can be controlled by applying drugs. The purpose of treating psoriasis can be achieved. It is mainly applied to punctate psoriasis, common psoriasis and some erythrodermic type and pustular psoriasis accompanied by upper respiratory tract infection, and the corresponding antibiotics or antibacterial drugs effective against Streptococcus haemolyticus can be used, such as penicillin, erythromycin and cephalosporin. 2. Retinoic acid class: Avia is effective in the treatment of plaque, pustular, palmoplantar, droplet and erythrodermic psoriasis. Preferred treatment: generalized pustular psoriasis, erythrodermic psoriasis; combined application with other treatments: palmoplantar pustulosis, generalized plaque psoriasis; separate therapy or adjuvant therapy: arthritic psoriasis. 3.Cyclosporine: it has definite efficacy on psoriasis. It is relatively safe to strictly follow the dermatological application dose <5mg.kg/d. Nephrotoxicity is its main adverse effect. 4. Glucocorticoids: The application of glucocorticoids may lead to erythrodermic type or pan-pustular psoriasis. Therefore, they should only be applied when deemed absolutely necessary by the dermatologist. Indications: Erythrodermic psoriasis that is difficult to control; generalized pustular psoriasis where other drugs are ineffective or contraindicated; acute polyarthritic psoriasis that can cause severe joint damage. 5. Other drugs that may be applied: salazosulfapyridine, tacrolimus, aminophenazone, methylsulfonamides, levamisole, transfer factor, colchicine, vitamins.