Mr. Chen, in his early forties, had acute herpes zoster on his front chest, back and inner right upper arm three years ago, and the lesions healed quickly after treatment at a local hospital dermatology department, but unfortunately the disease did not end there. For the past three years, he has been experiencing pain in the skin of the original rash area all the time. The burning, tightening and pins-and-needles pain is excruciating for the tall and sturdy Mr. Chen, and the touch of water in the shower can suddenly aggravate the pain. The chronic pain disturbed his sleep, affected his work and daily life, and made him extremely depressed. When a sad-looking Mr. Chen came into my office, after listening to his story and doing some physical examination, the diagnosis came out: postherpetic neuralgia (PHN). He became the youngest PHN patient I have seen in recent years …… Can PHN be avoided as much as possible by giving enough attention to shingles as early as the acute phase? As a pain physician, it is possible to give a definite answer, I think.