The treatment of IgA Nephropathy with Mild Tethered Hyperplasia includes non-immunosuppressant therapy, glucocorticoid therapy, immunosuppressant therapy and so on. 1. Non-immunosuppressant therapy: If patients with IgA nephropathy with mild thylakoid hyperplasia have symptoms such as proteinuria and elevated blood pressure, angiotensin-converting enzyme inhibitor/angiotensin II receptor antagonist, such as captopril, valsartan, etc., can be used to lower the blood pressure and reduce the urinary protein. 2. Glucocorticoid therapy: If a large amount of proteinuria occurs, it is usually necessary to take a sufficient amount of oral hormone therapy, such as prednisone and methylprednisolone, etc., and usually the patient can be relieved of urinary protein in a short period of time. 3. Immunosuppressant therapy: patients who are not sensitive to hormones can also use immunosuppressant therapy, commonly used drugs are cyclosporin A, cyclophosphamide and so on. All of the above drugs should be used under the guidance of a doctor, do not self-medication. It is recommended that patients go to the hospital in time and follow the standardized treatment.