Neonatal jaundice of 15.5mg/dl is usually pathologic jaundice, which is more serious and requires prompt treatment. Neonatal jaundice is a common disease of newborns, more than 80% of newborns can appear skin yellowing and other symptoms, more than 5~7mg/dl can be seen obvious jaundice manifestation, need to go to the hospital in time. Physiological jaundice usually appears late and subsides quickly, newborns are in good condition, usually not serious, and can subside naturally, and when it reaches the standard of phototherapy, it needs to be treated with light therapy. Pathological jaundice appears early and subsides late, and requires prompt identification of the cause and prompt treatment to avoid bilirubin encephalopathy. Common treatments include phototherapy, medication, blood exchange therapy or other treatments. Neonatal jaundice should be treated under the guidance of a doctor, and daily attention should be paid to the newborn’s skin and sclera staining, and the child should be kept warm.