The main items of the five items of hepatitis B that patients refer to as the three systems of hepatitis B include hepatitis B surface antigen, hepatitis B surface antibody, hepatitis B e antigen, hepatitis B e antibody and hepatitis B core antibody. If a patient has been vaccinated and has positive hepatitis B surface antibody, the titer can be greater than 10mIU/L. Such patients mostly have self-protection mechanism and are less likely to be infected with chronic viral hepatitis B. However, in the case of chronic viral hepatitis B, the hepatitis B triple system mostly indicates that the hepatitis B surface antigen is positive and can appear as major triplets as well as minor triplets. The so-called major triplet, that is, hepatitis B surface antigen positive, hepatitis B e antigen positive and hepatitis B core antibody positive. If these three are positive, the patient should be considered to have replication of the hepatitis B virus, and it is necessary to check the hepatitis B DNA and liver function to see if there is any replication of the virus and whether there is any damage to liver function. If there is, it is recommended to actively consider oral entecavir or tenofovir antiviral, or choose to inject interferon for six months and a year, some hepatitis B patients may turn into carriers. If you check the hepatitis B three system, suggesting that the hepatitis B surface antigen, hepatitis B e antibody and hepatitis B core antibody is positive, at this time, most of the consideration for the small three positive, small three positive suggests that the patient hepatitis B virus replication is less likely, check the hepatitis B DNA, the patient more than no hepatitis B virus replication. If there is no liver function damage, you can continue to observe and recheck the hepatitis B three systems, hepatitis B DNA and liver function every six months or a year.