There is no way to directly determine which effect of metronidazole gel and fusidic acid is good, the effect of the patient’s medication and the severity of the disease and their own constitution, need to be under the guidance of the doctor to use the drug. 1. Metronidazole gel: Metronidazole gel belongs to the anti-anaerobic drugs, can be used for local treatment of inflammatory papules, impetigo, rosacea erythema, etc., can inhibit the metabolism of bacteria, to help recovery. Some patients may experience dry skin and skin irritation after using the drug, which usually recovers on its own, but pregnant women and breastfeeding patients are prohibited. 2. Fusidic acid: Fusidic acid is commonly used in clinical formulations such as cream, eye drops, oral suspension, etc. It can treat infections caused by fusidic acid-sensitive bacteria, and can inhibit bacterial protein synthesis to achieve antibacterial effect. Adverse reactions such as rash and itching may occur after use, and usually recover spontaneously after stopping the drug, but it is forbidden for patients who are allergic to fusidic acid. Patients must follow the doctor’s instructions in accordance with the course of treatment and dosage of the drug, do not blindly choose their own drugs.