Whether a newborn born with positive maternal syphilis antibodies requires treatment depends on whether the newborn is diagnosed with congenital syphilis, and newborns diagnosed with congenital syphilis require treatment.
If the neonate is born with positive IgM antibodies or a serum syphilis spirochete antigen serologic test titer ≥ 4 times the mother’s pre-delivery titer and a positive syphilis spirochete antigen serologic test, the diagnosis of congenital syphilis can be confirmed, and treatment is required, usually with benzylpenicillin G.
Infants can not be diagnosed as congenital syphilis at birth, any follow-up found RPR (rapid plasma reactive element ring card test) from negative to positive or titer rise, combined with positive syphilis spirochete antigen serology test, can be diagnosed as congenital syphilis, is also required to apply benzylpenicillin G to treat.
Pregnant women with positive syphilis should undergo regular labor and delivery examinations, and the newborn should be examined and treated in a timely manner as prescribed by the doctor after delivery.