Mild intestinalized atypical hyperplasia may deteriorate within one year if it is not treated according to the doctor’s prescription and lifestyle improvement, but the condition is relatively less likely to deteriorate if it is actively treated and has a regular and healthy diet. Gastric mucosal atypical hyperplasia, also known as atypical hyperplasia, refers to the gastric mucosa cellular atypia, glandular structure disorders, belongs to the pre-cancerous lesions, is divided into light, medium and severe. Mild to moderate atypical hyperplasia is mainly treated by removing Helicobacter pylori infection, oral acid suppressants, gastrointestinal mucosal protectants and other medications, healthy diet and life, and regular review and follow-up, while severe cases are recommended to have immediate microscopic or surgical intervention. According to clinical research statistics, gastroscopy follow-up found that the cancer rate of mild heterotrophic hyperplasia is 2.53%, moderate is 4%-8%, and severe is 10%-83%. Therefore, the probability of gastric mucosa mild intestinal atypical hyperplasia worsening in one year is low, and it is recommended to actively follow the doctor’s instructions for treatment, and to avoid further deterioration of the disease with a regular and light diet. The mild enteric atypical hyperplasia of gastric mucosa has a certain chance to deteriorate and become cancerous, adhere to standardized treatment, good lifestyle and relaxation is conducive to the improvement of the disease.