For the treatment of Helicobacter pylori, the efficacy of proprietary pills is not guaranteed and is generally not used. Clinically, quadruple therapy is the mainstay of treatment, i.e., two antibiotics plus a proton pump inhibitor and bismuth. 1. antibiotics: common amoxicillin, clarithromycin, metronidazole, tetracycline, etc., need to choose any two of these drugs. If not allergic to penicillins, amoxicillin plus other antibiotics are preferred. If allergic to penicillins, tetracycline plus furazolidone can be chosen. 2. Proton pump inhibitors: Proton pump inhibitors include omeprazole, rabeprazole and pantoprazole, which can inhibit the secretion of gastric acid. 3. Bismuth: Bismuth, including colloidal bismuth pectin and bismuth potassium citrate, is a gastric mucosal protection drug, which can form a sol in gastric juice after oral intake to isolate gastric acid and protect the damaged mucosa. If the examination found that there is Helicobacter pylori infection, you need to go to the local regular hospital, under the guidance of the doctor to take quadruple therapy treatment, avoid self-medication.