Patients with pain inside the ears after a cold mainly consider the following aspects: First, after a cold, the patient’s pharyngeal cavity and nasal cavity mucosa will produce inflammation, the five senses are connected, the pharyngeal mucosa has inflammation, which may involve the patient’s middle ear cavity to form otitis externa or otitis media, so they will feel pain inside the ears. If the patient has a particularly large amount of nasal discharge, otitis media will form after blowing the nose hard, and there will be a lot of inflammatory exudate inside the middle ear cavity, and the patient will also have a significant pain sensation. Secondly, it is considered that fever can occur after a cold, leading to the formation of inflammation and swelling of the external ear canal. In such a case, it is important to actively treat the symptoms to alleviate the patient’s ear pain. The common antibiotic used clinically is cefprozil tablets. A clear allergy history is needed before using the drug, and it is best to use lomefloxacin hydrochloride ear drops inside the ear for anti-inflammatory purposes.