Blood uric acid 490μmol/L generally cannot be self-cured, but uric acid levels can be controlled by medication, diet and exercise to avoid complications such as gouty arthritis and gouty stones. Patients with non-same day 2 times fasting blood uric acid concentration higher than 420μmol/L can be diagnosed as hyperuricemia, and hyperuricemia generally can not be self-cured, but can be controlled by medication to control the level of uric acid, which commonly used uric acid-lowering drugs include febuxostat, benzbromarone and so on. Diet, hyperuricemia patients need to pay attention to low purine diet, avoid animal offal, seafood, alcoholic beverages and other diets, cardiac and renal function is normal need to ensure that the daily water consumption of at least 2L. Exercise, patients with hyperuricemia can properly carry out aerobic exercise to improve metabolism and weight control to achieve the purpose of controlling uric acid. Drugs should be used under the guidance of a physician, it is recommended that patients with uric acid 490 μmol / L to the rheumatology and immunology department or endocrinology department of regular hospitals, and follow the doctor’s instructions for treatment.